Conserved domain of PF1684

The PF1684 protein was homological analyzed by the Conserved Domain Database¹. The acetylglutamate kinase was compared among different species. Some of the results are shown in below²

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
consensus     1 RGKTIVIKLGGSAMEDENLLEAFASDIALLKSVGI-----RP-VVVHGGGPQIDEMLAKLGIEPEFVKG-----LRVTDA 69
query         1 ---MRVVKIGGSVISMLEN---------LWRENGIseilgNS-VIVHGGSRHVDELSRKMGVKIEKLTSpsgvtFRRTTK 67
1GS5_A        1 MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQ-----RPlVIVHGGGCVVDELMKGLNLPVKKKNG-----LRVTPA 70
gi 14520658   1 MIQMRVIKVGGSVVPM-------LDK-ILDTSSLH-----GNsIIVHGGSRYVDEMARKLGVKVERLVSpsgvmFRRTTR 67
gi 18313660   1 ---MIVVKIGGSVVCKD------ASKVIQNLPKYA-----DRaVVIHGGGCLVNELLKRMGIEPKFLTHpgglvSRYTDW 66

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
consensus    70 ETLEVVEMVLGGTVNKEIVARLSKHGGQAVGLSGVDGNLVTAKKL--------DVDDG---------VDLGYVGEIRKVN 132
PF1684        68 EVLKVYVAAMI-RANKEIVEFLRNQGINAIGLTGLDRELIIGERKklikavinGRVVA---------IRDDYSGVIKKVN 137
1GS5_A       71 DQIDIITGALAGTANKTLLAWAKKHQIAAVGLFLGDGDSVKVTQL--------DEE-------------LGHVGLAQPGS 129
gi 14520658  68 RVLDVYVAALM-RANRELVSFLRERGIDAIGVSGLD-GVVLAKRK--------KLVkavvng-kviairDDYSGVIKSIN 136
gi 18313660  67 ETLKVFVMAMG-WINKYIVASLHGLGVQALGLTGADLGVVVAKRK--------ERVlvidergrqrvvdGGYVGKIAEIR 137

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
consensus   133 PELIERLLDNGAIPVIAPIAVD-E-DGETLNVNADTAAGALAAALKAEKLILLTDVPGVLDDKGDpsLISELDAEEAEEL 210
PF1684       138 TQILREYLKIGT-PVIASIAYD-PiENTPLNVDGDKVAYHVALAMDAKELYFLSDTA-FMAGGK---VVSELPADEIEKY 211
1GS5_A      130 PKLINSLLENGYLPVVSSIGVT-D-EGQLMNVNADQAATALAATLGAD-LILLSDVSGILDGKGQ--RIAEMTAAKAEQL 204
gi 14520658 137 V-TLLKNYLKVgIPVIASIAYDpE-ENVPLNVDGDKVAYHVAIAMKAKeLRFLSDTA-FLIDGN---VVERIPLEDFDEY 210
gi 18313660 138 ----VDKLTPPpLKVLAPVAVS-E-KGELLNIDGDQLAFDVAREAKAErLILLSDVEGLILGGK---VVPRLTPEEAEKL 208

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*..
consensus   211 IEQGIITGGMIPKVEAALEALESGVRRVHI--ISGRVPHSlLLELFTRDGIGTMIVR 265
PF1684       212 LIF--AKGGMKKKLLMAKEAINSGIKNVVIegLNGRTviy----------------- 249
1GS5_A      205 IEQGIITDGMIVKVNAALDAARTLGRPVDI--ASWRHAEQ-LPALFNGMPMGTRILA 258
gi 14520658 211 LR--YAGGGMKKKLMMARKALESGVKKVVI---EGLNGRTvIS-------------- 248
gi 18313660 209 VKSEEVRGGMKRKLLMASEAAKLGI-EVVI--SSGLVDSPiDAALNGAGTHIIKNI- 261